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Health benefits of platycodon grandiflorum extract

Feb 5, 2024

1. Eliminate phlegm, relieve cough, promote lung qi

The effectiveness of some biologically active substances in Platycodon grandiflorum has been successively confirmed in scientific research. One of the active substances, called Platycodin D, can increase the release of mucin in cultures of epithelial cells on the tracheal surface. Its effect is stronger than ATP (an effective mucin secretagogue) and ambroxol (a kind of Mucolytic drug), showing a strong expectorant effect. Platycodon grandiflorum, another saponin called CKS or PA, can inhibit the development of respiratory tract inflammation by reducing allergic reactions.

 

2. Enhance immunity

Platycodon grandiflorum extract can enhance cell viability and has an immune-enhancing effect on suppressed immune spleen cells. Tests have shown that a variety of immune factors have increased, including natural killer cells and cytotoxic T lymphocytes, important immune stimulating cytokines and immunoglobulins in spleen cells. Platycodon grandiflorum can increase immune stimulating cytokines such as TNF-α, IFN-γ, IL-2, IL-12 and immunoglobulins (IgG and IgA) in spleen cells, and reduce inflammation markers such as MPO, IL-6, TNF -α, NF-κB. In addition, it helps the white blood cell, neutrophil and lymphocyte counts to return to normal, and protects the spleen and thymus, an important immune organ, from damage.

 

3. Anti-inflammatory

Studies have shown that in animal experiments, Platycodon grandiflorum can reduce excessive white blood cells (total number of white blood cells) and the percentage of neutrophils in lung fluid, as well as inflammation markers, and also increase the antioxidant activity of superoxide dismutase (SOD) in lung fluid. To prevent acute lung injury. Platycodon grandiflorum has the dual effects of anti-inflammatory and immune enhancement, which is very beneficial to lung health.

 

4. Other functions

The chemical components of Platycodon grandiflorum include saponins, flavonoids, polyacetylenes, sterols, phenols and other biologically active compounds. Scientific research shows that Platycodon grandiflorum also has other effects, including anti-tumor, anti-oxidant, anti-diabetic, anti-obesity, liver and cardiovascular protection.

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